One in fifty births in New Zealand are now the result of fertility treatments. Yet in spite of the high profile of fertility treatments such as in vitro fertilisation most of the interventions have been poorly researched. Many treatments have been introduced without evaluation by randomised controlled trials. This is particularly so in the case of add-ons for in vitro fertilisation. In response to these concerns a body of work has been undertaken to improve the reporting and conduct of clinical trials as well as highlight the gaps in the knowledge base for fertility treatments. This presentation will showcase the highs and lows of infertility research.