Male infertility is a medical condition affecting one in 20 men in the western world1,2 and accounts solely, or in a contributory way, for ~50% of couples attending assisted conception (AC)3. The common approach to overcome male-factor infertility is through Assisted conception, which treats the symptom, not the cause. Several efforts have been made to treat males with poor semen quality, with promising results. For example, in clinical trials, (many dating back to the 1980s) scrotal cooling is an effective proven alternative form of AC that improves semen quality and natural pregnancy rates. For example, trials performed in 25 infertile men showed that in 18 men (70%), semen parameters improved with scrotal cooling18, and 6 (24%) went on to conceive a natural pregnancy during the 14-week scrotal cooling regime, despite the fact they had been “trying” to conceive for 3-8 years previously19-21. A second trial involving 64 men, showed improvements in semen parameters in 66% of cases and a pregnancy rate of 27%23 within 16 weeks of scrotal cooling. Despite the success of these studies, scrotal cooling has not been taken up as a therapeutic option due to three major issues. These include 1) some devices have been too bulky for practical day-to-day use, 2) some devices have been based on cold damp cloths, which is not practical for being worn under clothes 3) some devices need access to refrigerator/freezer throughout the day. Here we investigate how this can be overcome.